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US 11,912,678 B2Granted
LRRK2 inhibiting compounds and use thereof for treating neurodegenerative diseases
AssigneeConsejo Superior de Investigaciones Cientificas
InventorsAna Martinez Gil, Carmen Gil Ayuso-Gontan, Josefa Zaldivar Diaz De Bonilla, Rocio Benitez Fernandez
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Abstract
The present invention relates to a series of compounds having a structural benzothiazole-benzamide core with capacity to inhibit the LRRK2 enzyme, due to which the invention also relates to the use of these compounds for treating neurodegenerative diseases in which this enzyme is involved, such as Parkinson's Disease or Alzheimer's Disease.
Claims14
A compound of formula (I):
- wherein R1 is selected from H, C1-C6 alkyl, halogen, CF3 and —O—C1-C6 alkyl.
Dependencies are inferred from the claim text.