Combined bio-artificial liver support system
AssigneeSouthern Medical University Zhujiang Hospital
InventorsYi Gao, Mingxin Pan, Lei Feng, Yang Li, Lei Cai, Guolin He, Jun Weng, Qing Peng
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Abstract
A combined bio-artificial liver support system, includes branch tubes that are connected in sequence: a blood input branch tube, an upstream tail end, a first plasma separation branch tube comprising at least a first plasma separator, a non-biological purification branch tube comprising at least a plasma perfusion device and a bilirubin adsorber, a biological purification branch tube comprising at least a hepatocyte culture cartridge assembly, and a plasma return branch tube, a downstream tail end of which is set as a blood output end.
Claims14
A combined bio-artificial liver support system, comprising a plurality of branch tubes that are connected in sequence:
- a blood input branch tube, an upstream tail end of which is set as a blood input end, a first plasma separation branch tube comprising at least a first plasma separator, a non-biological purification branch tube comprising at least a plasma perfusion device and a bilirubin adsorber, a biological purification branch tube comprising at least a hepatocyte culture cartridge assembly, and a plasma return branch tube, a downstream tail end of which is set as a blood output end, wherein by means of three-way devices, the first plasma separation branch tube is connected to inlet ends of the biological purification branch tube and the non-biological purification branch tube, an outlet end of the non-biological purification branch tube is connected to the biological purification branch tube, and the outlet end of the non-biological purification branch tube is connected to the plasma return branch tube, each of the three-way devices comprises a three-way joint and branches respectively connected to the three-way joint, and at least two said branches are respectively provided with a flow restricting member and a coupling member.
Dependencies are inferred from the claim text.