Strong base-initiated N-carboxyanhydride rapid ring-opening polymerization method
AssigneeEast China University of Science and Technology
InventorsRunhui Liu, Yueming Wu
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Abstract
The present invention relates to a strong base-initiated N-carboxyanhydride rapid ring-opening polymerisation method. Specifically, the method comprises steps of: performing a polymerisation reaction with one or more amino acid N-carboxyanhydride monomers in an organic solvent in the presence of an initiator, so as to form an amino acid polymer, wherein the initiator is selected from the following group: LiHMDS, NaHMDS, KHMDS, or a combination thereof. The method significantly increases the speed of traditional NCA polymerisation and prepares a long-chain polymer, and the prepared amino acid polymer may be used as an anti-bacterial material, an anti-tumour material, a tissue engineering scaffold or a self-assembling material.
Claims14
A method for preparing an amino acid polymer comprising the step of:
- polymerizing one or more amino acid N-carboxyanhydride monomers in an organic solvent in the presence of an initiator, so as to form the amino acid polymer;
- wherein the initiator is selected from the group consisting of LiHMDS, NaHMDS, KHMDS, and a combination thereof.
Dependencies are inferred from the claim text.