Anti-thrombogenic medical devices and methods
AssigneeCovidien LP
InventorsXiaodong Ma, Min-Shyan Sheu, Lincoln Eramo, John Wainwright, Junwei Li
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Abstract
Methods for forming an expandable tubular body having a plurality of braided filaments including a first filament including platinum or platinum alloy and a second filament including cobalt-chromium alloy. The methods include applying a first phosphorylcholine material directly on the platinum or platinum alloy of the first filament and applying a silane material on the second filament followed by a second phosphorylcholine material on the silane material on the second filament. The first and second phosphorylcholine materials each define a thickness of less than 100 nanometers.
Claims20
A medical device, comprising:
- a vascular device comprising a sidewall having a plurality of pores, wherein the vascular device is configured to be implanted in a blood vessel, and wherein at least a portion of the sidewall comprises:
- a substrate comprising at least one of cobalt, cobalt alloy, chromium, chromium alloy, nickel, or nickel alloy;
- a silane layer comprising a silane material on the substrate;
- and
- an outer coating comprising a phosphorylcholine material on the silane layer, wherein the outer coating defines a layer thickness of less than 10 nanometers.
A method comprising:
- applying a silane layer comprising a silane material on a substrate of a sidewall of a vascular device configured to be implanted in a blood vessel, the sidewall having a plurality of pores, wherein the substrate comprises at least one of cobalt, cobalt alloy, chromium, chromium alloy, nickel, or nickel alloy;
- and
- applying an outer coating comprising a phosphorylcholine material on the silane layer, wherein the outer coating defines a layer thickness of less than 10 nanometers.
Dependencies are inferred from the claim text.