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US 11,899,026 B2Granted
ABO blood group point-of-care chip testing
AssigneeUniversity of Rochester, Rochester Institute of Technology
InventorsMajed J. Refaai, Steven W. Day
Life of this patent
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Abstract
The present invention provides point-of-care blood typing devices. The devices require only a small sample of blood and are able to provide results within minutes. The devices are capable of identifying A, B, AB, and O type blood. The devices are also capable of identifying blood that is positive (+) or negative (−) for the D antigen.
Claims19
A portable blood typing device comprising:
- a body having an exterior surface;
- a port formed in the exterior surface of the body;
- one or more microchannels embedded in the body, each microchannel extending from the port to an air hole formed in the exterior surface of the body;
- and
- one or more reservoirs embedded in the exterior surface of the body arranged in an X array pattern, each reservoir being fluidly connected to each microchannel;
- wherein a first reservoir connected to a first microchannel contains a fluid composition comprising a first probe that binds to antigen A, a second reservoir connected to a second microchannel contains a fluid composition comprising a second probe that binds to antigen B, a third reservoir connected to a third microchannel contains a fluid composition comprising a third probe that binds to antigen D, and a fourth reservoir connected to a fourth microchannel contains a fluid;
- and wherein the fluid connection between each reservoir and each microchannel is obstructed by a breakable seal.
4 more elements
Dependencies are inferred from the claim text.