Mixer for liquid chromatography
AssigneeWaters Technologies Corporation
InventorFabrice Gritti
Life of this patent
Estimating the term…
Abstract
Described is a mixer for a liquid chromatography system. The mixer includes a flow distributor, a mixing disk and a flow collector. The mixer includes an inlet face, an outlet face and a plurality of channels each having an inlet end at the inlet face and an outlet end at the outlet face. The channels have a flow direction anisotropy between the inlet and outlet faces. A compositional solvent stream received at the flow distributor is distributed across the inlet face of the mixing disk and the flow collector collects the distributed solvent composition stream after passing through the mixing disk. The mixing disk may include a dispersive medium having a random porous structure. A retention time distribution of the mixer may depend on the structure of the channels between the inlet and outlet faces of the mixing disk.
Claims25
A mixer for a liquid chromatography system comprising:
- a flow distributor having a distributor inlet port having a distributor inlet cross-section and a distributor outlet port having a distributor outlet cross-section which is greater than the distributor inlet cross-section, the distributor inlet port configured to receive a flow of a compositional solvent stream and the distributor outlet port configured to provide the compositional solvent stream distributed across the distributor outlet cross-section;
- a mixing disk having an inlet face, an outlet face and a plurality of channels each having an inlet end at the inlet face and an outlet end at the outlet face, the inlet face being in communication with the distributor outlet port, the channels having a flow direction anisotropy between the inlet and outlet faces;
- and
- a flow collector having a collector inlet port having a collector inlet cross-section and a collector outlet port having a collector outlet cross-section which is less than the collector inlet cross-section, the collector inlet port being in communication with the outlet face of the mixing disk to receive the flow of the compositional solvent stream after passing through the mixing disk.
Dependencies are inferred from the claim text.