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US 11,897,931 B2Granted
MANP analogues
AssigneeMayo Foundation for Medical Education and Research
InventorJohn C. Burnett, Jr.
Life of this patent
Estimating the term…
Abstract
Analogues of an alternatively spliced form of atrial natriuretic peptide (MANP) that exhibit pGC-A gain of function and can be used to treat cardiorenal and metabolic disease are described herein.
Claims12
An isolated nucleic acid encoding a natriuretic polypeptide comprising the amino acid sequence set forth in SEQ ID NO:5.
An isolated nucleic acid encoding a natriuretic polypeptide comprising the amino acid sequence set forth in SEQ ID NO:3 or SEQ ID NO:6.
An isolated nucleic acid encoding a natriuretic polypeptide comprising the amino acid sequence set forth in SEQ ID NO:15.
Dependencies are inferred from the claim text.