# US 11,896,972 B2 · Device having a first chamber for receiving a body fluid

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- Number: US 11,896,972 B2
- Document ID: US11896972B2
- Status: Granted
- Kind: B2
- Application number: 16/652,620
- Filed: 2018-10-10
- Published: 2020-07-30
- Granted: 2024-02-13
- Earliest claimed: 2017-10-11
- Assignees: Orthogen AG
- Applicants: Orthogen AG
- Inventors: Nina Breidenbach; Julio Reinecke; Julien Troillet; Peter Wehling; Julia Heindirk
- Web page: https://patentgrep.com/patent/US11896972B2

## CPC

- B01L 3/5021: {Test tubes specially adapted for centrifugation purposes}
- A61M 1/029: {Separating blood components present in distinct layers in a container, not otherwise provided for (containers for storing blood or blood components A61J1/05; sampling or analysing blood by separating blood components G01N33/491)}
- B01L 3/502: {with fluid transport, e.g. in multi-compartment structures}
- A61M 1/3693: {using separation based on different densities of components, e.g. centrifuging}
- B01L 2200/026: Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L 2200/0621: Control of the sequence of chambers filled or emptied
- B01L 2300/044: pierceable, e.g. films, membranes
- B01L 2300/045: whereby the whole cover is slidable
- B01L 2300/0672: Integrated piercing tool
- B01L 2300/0832: cylindrical, tube shaped
- B01L 2300/087: Multiple sequential chambers
- B01L 2400/0409: centrifugal forces
- B01L 2400/0478: pistons
- B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

The invention relates to an apparatus for receiving a body fluid, wherein the apparatus comprises a first chamber with a displaceable wall and a second chamber of a constant effective size, said second chamber being movable with respect to the displaceable wall, wherein the apparatus is designed to connect the first chamber and the second chamber during a longitudinally axial movement of the second chamber with respect to the displaceable wall and to transfer body fluid from the first chamber to the second chamber during a movement of the second chamber together with the displaceable wall.

## Claims

### Claim 1

An apparatus for receiving a body fluid, wherein the apparatus comprises:
a) a first chamber that can receive the body fluid, the first chamber having a cylindrical section, designed as a cylinder, and a displaceable wall, the first chamber further having an opening on a connecting part, which lies opposite the displaceable wall, the connecting part being designed to be connected to an external element,
the displaceable wall having an opening, which can be selectively opened or closed by means of a barrier,
wherein the displaceable wall is connected to a guide, the guide and the displaceable wall being arranged in the cylinder in such a way that the guide and the displaceable wall can be displaced together in the cylinder, wherein the guide is arranged on the side which is opposite the opening of the first chamber, and
b) a second chamber which is mounted in or on the guide and that can receive the body fluid, the second chamber being closed by a sealing means, the second chamber having a constant effective size,
wherein the size of the first chamber can be increased in order to draw the body fluid into the first chamber by moving the displaceable wall,
wherein a movement of the second chamber within the guide is prevented by means of a blocking means, which can be removed, and after removing the blocking means, a movement of the second chamber relative to the guide and the displaceable wall can take place,
the apparatus is designed to connect the first chamber and the second chamber to transfer body fluid from the first chamber to the second chamber via a longitudinally axial movement of the second chamber with respect to the displaceable wall in a first step, in which the sealing means of the second chamber is pierced by an opener, and in a next step, in which the second chamber moves together with the displaceable wall, the opening of the first chamber in the displaceable wall is opened.

### Claim 2 (depends on 1)

The apparatus as claimed in claim 1, wherein the two chambers are closed to the environment after receiving the body fluid.

### Claim 3 (depends on 1)

The apparatus as claimed in claim 1, wherein the barrier is designed as a check valve or “duckbill valve” or as an umbrella valve, which is arranged on the outside of a wall of the first chamber.

### Claim 4 (depends on 1)

The apparatus as claimed in claim 1, wherein the opener is arranged between the first and second chamber.

### Claim 5 (depends on 1)

The apparatus as claimed in claim 1, wherein a selection means which is designed as a filter is arranged between the first and second chamber.

### Claim 6 (depends on 1)

The apparatus as claimed in claim 1, wherein a septum is provided for reclosing the first chamber after filling.

### Claim 7 (depends on 1)

The apparatus as claimed in claim 1, wherein a substance, enlarging the inner surface area of the first chamber, is arranged in the first chamber, the substance having an inducing effect on the formation of autologous proteins.

### Claim 8 (depends on 1)

The apparatus as claimed in claim 1, wherein the second chamber has a negative pressure or an air outlet.

### Claim 9 (depends on 1)

The apparatus as claimed in claim 1, wherein the movement of the displaceable wall is limited by means of a stop element.

### Claim 10 (depends on 1)

The apparatus as claimed in claim 1, wherein the apparatus can be filled in a sterile manner.

### Claim 11 (depends on 1)

The apparatus as claimed in claim 1, wherein the first chamber comprises a biologically active substance.