# US 11,896,849 B2 · Subject positioning systems and methods > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,896,849 B2 - Document ID: US11896849B2 - Status: Granted - Kind: B2 - Application number: 17/649,366 - Filed: 2022-01-30 - Published: 2022-05-19 - Granted: 2024-02-13 - Earliest claimed: 2018-12-29 - Assignees: Shanghai United Imaging Healthcare Co., Ltd. - Applicants: Shanghai United Imaging Healthcare Co., Ltd. - Inventors: Yifeng Wang; Yige Zhang - Web page: https://patentgrep.com/patent/US11896849B2 ## CPC - A61N 5/1049: {for verifying the position of the patient with respect to the radiation beam} - A61N 5/1067: {in real time, i.e. during treatment} - A61N 5/107: {in real time, i.e. during treatment} - G03H 1/02: Details {of features involved during the holographic process; Replication of holograms without interference recording} - G03H 1/2249: {Holobject properties} - G03H 5/00: Holographic processes or apparatus using particles or using waves other than those covered by groups G03H1/00 or G03H3/00 for obtaining holograms; Processes or apparatus for obtaining an optical image from them (G03H1/22 takes precedence; construction of electron microscopes H01J37/26; {investigating or analysing materials by the use of microwaves G01N22/00, by the use of particles wave or X-rays G01N23/00, G21K7/00}) - G06T 7/0012: {Biomedical image inspection} - G06T 7/246: using feature-based methods, e.g. the tracking of corners or segments - A61N 5/1037: {taking into account the movement of the target, e.g. 4D-image based planning} - A61N 2005/105: {using a laser alignment system} - A61N 2005/1051: {using an active marker} - A61N 2005/1055: {using magnetic resonance imaging [MRI]} - A61N 2005/1056: {by projecting a visible image of the treatment field} - A61N 2005/1059: {using cameras imaging the patient} - A61N 2005/1061: {using an x-ray imaging system having a separate imaging source} - A61N 2005/1062: {using virtual X-ray images, e.g. digitally reconstructed radiographs [DRR]} - A61N 2005/1063: {maintaining the position when the patient is moved from an imaging to a therapy system} - A61N 2005/1076: {using a dummy object placed in the radiation field, e.g. phantom} - G03H 2210/30: 3D object - G06T 2207/30004: Biomedical image processing - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) - G03H: HOLOGRAPHIC PROCESSES OR APPARATUS (holograms, e.g. point holograms, used as ordinary optical elements G02B5/32; producing stereoscopic or other three-dimensional effects G02B30/00; diffraction-grating systems G02B27/44; systems using moiré fringes G02B27/60; optical logic elements G02F3/00; stereo-photography G03B35/00; photosensitive materials or processes for photographic purposes G03C; {stereo-photographic or similar processes G03C9/00}; apparatus for processing exposed photographic materials G03D; analogue computers performing mathematical operations with the aid of optical elements G06E3/00; authentication by radiation, of concealed information carried by holograms or diffraction gratings G06K19/16; holographic storage G11B7/0065, G11C13/04; {stereoscopic or other three dimensional effects in television systems H04N13/00}) - G06T: IMAGE DATA PROCESSING OR GENERATION, IN GENERAL ## Abstract Subject positioning systems and methods are provided. A method may include obtaining first information of at least part of a subject when the subject is located at a preset position, and determining, based on the first information, a first position of each of one or more feature points located on the at least part of the subject. The method may include obtaining, using an imaging device, second information of the at least part of the subject when the subject is located at a candidate position. The method may further include determining, based on the second information, a second position of each of the one or more feature points, a first distance between the first position and the second position for each feature point of the one or more feature points, and a target position of the subject based at least in part on the one or more first distances. ## Claims ### Claim 1 A method for positioning a subject, implemented on a computing device having one or more processors and one or more storage devices, the method comprising: obtaining a first three-dimensional (3D) surface image of at least part of a subject when the subject is located at a preset position; generating a virtual representation of the at least part of the subject based on the first 3D surface image; displaying the virtual representation of the at least part of the subject at the preset position and superimposing the virtual representation on the subject to mimic the at least part of the subject that is inside the subject; obtaining a second 3D surface image of the at least part of the subject when the subject is located at a candidate position; and determining, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject meets the requirement of a target position of the subject. ### Claim 2 (depends on 1) The method of claim 1, wherein the determining, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject meets the requirement of a target position of the subject, includes: determining, based on the first 3D surface image, a first position of each of one or more feature points located on the at least part of the subject; determining, based on the second 3D surface image, a second position of each of the one or more feature points; for each feature point of the one or more feature points, determining a first distance between the first position and the second position; and determining, based at least in part on the one or more first distances, whether the candidate position of the subject meets the requirement of the target position of the subject. ### Claim 3 (depends on 2) The method of claim 2, wherein the one or more feature points include at least a marker located on a surface of the subject, the marker indicating a region of interest (ROI) of the subject. ### Claim 4 (depends on 2) The method of claim 2, wherein the determining, based at least in part on the one or more first distances, whether the candidate position of the subject meets the requirement of the target position of the subject includes: determining whether the one or more first distances are less than a first threshold. ### Claim 5 (depends on 4) The method of claim 4, further includes: determining a target position of the subject based on a determination result of whether the one or more first distances are less than the first threshold. ### Claim 6 (depends on 5) The method of claim 5, wherein the determination result includes that at least one of the one or more first distances is less than the first threshold, and the determining the target position of the subject includes: designating the candidate position as the target position of the subject. ### Claim 7 (depends on 5) The method of claim 5, wherein the determination result includes that at least one of the one or more first distances exceeds the first threshold, and the determining the target position of the subject includes: adjusting the candidate position of the subject to an adjusted position such that, for each of the one or more feature points, a second distance between a third position of the feature point and the first position of the feature point is less than the first threshold, wherein the third position is obtained based on third information of the at least part of the subject, and the third information includes at least a third set of position data of the at least part of the subject; and designating the adjusted position as the target position of the subject. ### Claim 8 (depends on 2) The method of claim 2, further comprising: obtaining fourth information of the at least part of the subject using the imaging device at a time interval during a radiation session, the fourth information including at least a fourth set of position data of the at least part of the subject; determining, based on the fourth information, a fourth position of each of the one or more feature points; and causing, based on a third distance between the fourth position and the first position of each of the one or more feature points, a radiation assembly to perform a preset operation corresponding to the third distance. ### Claim 9 (depends on 8) The method of claim 8, wherein the causing, based on a third distance between the fourth position and the first position of each of the one or more feature points, a radiation assembly to perform a preset operation corresponding to the third distance includes: controlling an operation of the radiation assembly based on a second determination result of whether the third distance is less than the first threshold. ### Claim 10 (depends on 9) The method of claim 9, wherein the second determination result includes that the third distance exceeds the first threshold, and the controlling an operation of the radiation assembly based on a second determination result of whether the third distance is less than the first threshold includes: causing the radiation assembly to stop emitting radiation beams. ### Claim 11 (depends on 1) The method of claim 1, wherein the obtaining a second 3D surface image of the at least part of the subject when the subject is located at a candidate position includes: obtaining, using an imaging device, the second 3D surface image of the at least part of the subject when the subject is located at the candidate position. ### Claim 12 (depends on 11) The method of claim 11, wherein the imaging device includes a holographic projection device, and the obtaining the second 3D surface image of the at least part of the subject includes: obtaining first scanning data by causing the holographic projection device to image the subject using a millimeter wave; and obtaining the second 3D surface image based on the first scanning data. ### Claim 13 (depends on 1) The method of claim 1, further comprising: obtaining second scanning data by scanning a target area, wherein the target area includes the subject and a motion area of a radiation assembly; obtaining fifth information of the target area based on the second scanning data, the fifth information including at least a fifth set of position data of the target area; obtaining a motion trajectory of the radiation assembly; predicting, based on the fifth information and the motion trajectory, whether the subject and the radiation assembly are going to collide; and adjusting a position of the subject based on a prediction result of whether the subject and the radiation assembly are going to collide. ### Claim 14 (depends on 13) The method of claim 13, wherein the predicting, based on the fifth information and the motion trajectory, whether the subject and the radiation assembly are going to collide includes: determining, based on coordinates corresponding to the target area and coordinates corresponding to the motion trajectory of the radiation assembly, at least one distance; and generating, based on a determination result that the at least one distance is less than a threshold, a prediction result that the subject and the radiation assembly are going to collide. ### Claim 15 (depends on 1) The method of claim 1, wherein t the determining, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject satisfies a condition for radiation delivery, includes: determining the target position of the subject from one or more candidate positions based on an overlapping degree of the virtual representation of the at least part of the subject and the at least part of the subject. ### Claim 16 A system for positioning a subject, comprising: at least one storage device including a set of instructions or programs; and at least one processor configured to communicate with the at least one storage device, wherein when executing the set of instructions or programs, the at least one processor is configured to cause the system to perform operations including: obtaining a first three-dimensional (3D) surface image of at least part of a subject when the subject is located at a preset position; generating a virtual representation of the at least part of the subject based on the first 3D surface image; displaying the virtual representation of the at least part of the subject at the preset position and superimposing the virtual representation on the subject to mimic the at least part of the subject that is inside the subject; obtaining a second 3D surface image of the at least part of the subject when the subject is located at a candidate position; and determining, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject meets the requirement of a target position of the subject. ### Claim 17 (depends on 16) The system of claim 16, wherein to determine, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject meets the requirement of a target position of the subject, the at least one processor is further configured to cause the system to perform the operations including: determining, based on the first 3D surface image, a first position of each of one or more feature points located on the at least part of the subject; determining, based on the second 3D surface image, a second position of each of the one or more feature points; for each feature point of the one or more feature points, determining a first distance between the first position and the second position; and determining, based at least in part on the one or more first distances, whether the candidate position of the subject meets the requirement of the target position of the subject. ### Claim 18 (depends on 17) The system of claim 17, wherein the one or more feature points include at least a marker located on a surface of the subject, the marker indicating a region of interest (ROI) of the subject. ### Claim 19 (depends on 16) The system of claim 16, wherein the determining, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject satisfies a condition for radiation delivery includes: determining the target position of the subject from one or more candidate positions based on an overlapping degree of the virtual representation of the at least part of the subject and the at least part of the subject. ### Claim 20 A non-transitory computer readable medium storing instructions, the instructions, when executed by at least one processor, causing the at least one processor to implement a method comprising: obtaining a first three-dimensional (3D) surface image of at least part of a subject when the subject is located at a preset position; generating a virtual representation of the at least part of the subject based on the first 3D surface image; displaying the virtual representation of the at least part of the subject at the preset position and superimposing the virtual representation on the subject to mimic the at least part of the subject that is inside the subject; obtaining a second 3D surface image of the at least part of the subject when the subject is located at a candidate position; and determining, based on the displayed virtual representation of the at least part of the subject or the first 3D surface image and the second 3D surface image, whether the candidate position of the subject meets the requirement of a target position of the subject.