# US 11,896,703 B2 · Liquid lipid composite composition for improving hair condition > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,896,703 B2 - Document ID: US11896703B2 - Status: Granted - Kind: B2 - Application number: 17/041,300 - Filed: 2019-03-22 - Published: 2021-01-21 - Granted: 2024-02-13 - Earliest claimed: 2018-03-27 - Assignees: Amorepacific Corporation - Applicants: Amorepacific Corporation - Inventors: Jae Won Yoo; Minjin Kim; Yong Jin Kim; Jangwon Choi - Web page: https://patentgrep.com/patent/US11896703B2 ## CPC - A61K 8/63: Steroids; Derivatives thereof - A61K 8/361: {Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof} - A61K 8/37: Esters of carboxylic acids - A61K 8/42: Amides - A61K 8/68: Sphingolipids, e.g. ceramides, cerebrosides, gangliosides - A61K 8/922: {of vegetable origin} - A61Q 5/002: {Preparations for repairing the hair, e.g. hair cure} - A61Q 5/12: Preparations containing hair conditioners - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract Disclosed in the present specification is a liquid lipid composite composition comprising ceramide, cholesterol, a C10-30 unsaturated fatty acid having three or fewer double bonds, and natural oil or wax containing a C10-60 fatty acid ester or C10-60 fatty acid ester at a weight ratio of 1:0.03-3:2.5-12:0.3-6. The liquid lipid composite composition comprises a high content of ceramide and is present in a liquid state during storage at normal temperature, and thus can be easily applied as a formulation of a hair cosmetic composition. The liquid lipid composite composition, when used to treat hair, has excellent hair condition improving effects, such as improving the softness of the hair, enhancing the elasticity and strength of the hair, and increasing the shininess of the hair. ## Claims ### Claim 1 A liquid lipid composite composition which comprises ceramide, cholesterol, a C10-30 fatty acid, and a C10-60 fatty acid ester, or natural oil or wax containing a C10-60 fatty acid ester at a weight ratio of 1:0.3-3:12.5-12:0.3-6, wherein the ceramide is pseudoceramide wherein the C10-30 fatty acid is C10-30 unsaturated fatty acid having three or fewer double bonds. ### Claim 2 (depends on 1) The liquid lipid composite composition according to claim 1, wherein the pseudoceramide is a compound represented by the following Chemical Formula 1: wherein R is a C2-25 alkyl. ### Claim 3 (depends on 2) The liquid lipid composite composition according to claim 2, wherein R is C15H31. ### Claim 4 (depends on 1) The liquid lipid composite composition according to claim 1, wherein the C10-30 unsaturated fatty acid having three or fewer double bonds is at least one selected from the group consisting of oleic acid, erucic acid, nervonic acid, linoleic acid and linolenic acid. ### Claim 5 (depends on 1) The liquid lipid composite composition according to claim 1, wherein the C10-60 fatty acid ester is ethyl oleate. ### Claim 6 (depends on 1) The liquid lipid composite composition according to claim 1, wherein the natural oil or wax containing a C10-60 fatty acid ester is at least one selected from the group consisting of jojoba oil, bees wax, carnauba wax and candelilla wax. ### Claim 7 (depends on 1) The liquid lipid composite composition according to claim 1, which comprises 5-15 wt % of ceramide, 5-15 wt % of cholesterol, 40-60 wt % of a C10-30 unsaturated fatty acid having three or fewer double bonds, and 5-30 wt % of a C10-60 fatty acid ester, or natural oil or wax containing a C10-60 fatty acid ester, based on the total weight of ceramide, cholesterol, a C10-30 unsaturated fatty acid having three or fewer double bonds, and a C10-60 fatty acid ester, or natural oil or wax containing a C10-60 fatty acid ester. ### Claim 8 (depends on 1) The liquid lipid composite composition according to claim 1, which is present in a liquid state at room temperature. ### Claim 9 (depends on 1) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 1 to a subject in need thereof. ### Claim 10 (depends on 9) The method according to claim 9, wherein the improving a hair condition is an increase in hair elasticity and strength, an increase in hair shininess, or enhancement of hair softness. ### Claim 11 (depends on 1) The liquid lipid composite composition according to claim 1, which is a cosmetic composition. ### Claim 12 (depends on 1) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 1 to a subject in need thereof. ### Claim 13 (depends on 2) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 2 to a subject in need thereof. ### Claim 14 (depends on 3) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 3 to a subject in need thereof. ### Claim 15 (depends on 4) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 4 to a subject in need thereof. ### Claim 16 (depends on 5) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 5 to a subject in need thereof. ### Claim 17 (depends on 6) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 6 to a subject in need thereof. ### Claim 18 (depends on 7) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 7 to a subject in need thereof. ### Claim 19 (depends on 8) A method for improving a hair condition comprising administering an effective amount of the composition according to claim 8 to a subject in need thereof.