# US 11,896,698 B2 · Personal cleansing compositions and methods of stabilizing the microbiome > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,896,698 B2 - Document ID: US11896698B2 - Status: Granted - Kind: B2 - Application number: 15/763,920 - Filed: 2016-09-30 - Published: 2019-02-21 - Granted: 2024-02-13 - Earliest claimed: 2015-10-01 - Assignees: RB Health (US) LLC - Applicants: Rb Health (US) LLC - Inventors: Jessica Wilson; Sarah Frances de Szalay; Elizabeth Bruning; Rui Yang - Web page: https://patentgrep.com/patent/US11896698B2 ## CPC - A61K 8/442: {substituted by amido group(s)} - A61K 8/046: {Aerosols; Foams} - A61K 8/20: Halogens; Compounds thereof - A61K 8/345: {containing more than one hydroxy group} - A61K 8/365: Hydroxycarboxylic acids; Ketocarboxylic acids - A61K 8/39: Derivatives containing from 2 to 10 oxyalkylene groups - A61K 8/42: Amides - A61K 8/44: Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof - A61K 8/45: Derivatives containing from 2 to 10 oxyalkylene groups - A61K 8/463: {containing sulfuric acid derivatives, e.g. sodium lauryl sulfate} - A61K 8/86: Polyethers - A61K 31/047: having two or more hydroxy groups, e.g. sorbitol - A61K 31/095: Sulfur, selenium, or tellurium compounds, e.g. thiols - A61K 31/19: Carboxylic acids, e.g. valproic acid (salicylic acid A61K31/60) - A61K 31/765: Polymers containing oxygen - A61K 31/785: Polymers containing nitrogen - A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca - A61P 15/02: for disorders of the vagina - A61P 17/00: Drugs for dermatological disorders - A61P 17/16: Emollients or protectives, e.g. against radiation - A61P 31/02: Local antiseptics - A61P 31/04: Antibacterial agents - A61P 31/10: Antimycotics - A61Q 17/005: {Antimicrobial preparations} - A61Q 19/005: {Preparations for sensitive skin} - A61Q 19/10: Washing or bathing preparations - A61K 2800/75: Anti-irritant - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract A personal wash composition which provides an effective antimicrobial benefit against fungi, gram positive and gram negative bacteria, which composition comprises: a) from 0.1% to 10 wt % betaine surfactant, b) from 0.1% to 5.0 wt % lactic acid, c) from 0.1% to 20 wt % polyhydric C2-C6 alcohol, d) from 0% to 10 wt % alkyl polyethoxy carboxylate of the formula RO(CH2CH2O)kCH2COO−M+ wherein R is a C8-C22 alkyl, k is an integer from 0 to 20, and M is a soluble salt-forming cation, e) from 0% to 10 wt % alkyl polyethoxy amides of the formula RO(CH2CH2O)kCH2CONH2 wherein R is a C8-C22 alkyl, k is an integer from 0 to 20, f) >8 wt % alkyl ether sulphate, g) water, h) a pH of 3.8-4.5, i) 10-20 wt % total surfactant, j) from 0.1 to 10 wt % metal salt. ## Claims ### Claim 1 A personal wash composition comprising: from 1 wt % to 3 wt % betaine surfactant; from 2 wt % to 5.0 wt % lactic acid; from 10 wt % to 15 wt % glycerol; from 2 wt % to 7 wt % alkyl polyethoxy carboxylate; from 1 wt % to 3 wt % alkyl polyethoxy amides; greater than 8 wt % alkyl ether sulphate; water; a pH of 3.8-4.5; 10-20 wt % total surfactant; and 0.1 to 10 wt % metal salt, wherein the personal wash composition provides an effective antimicrobial benefit against fungi, gram positive bacteria, and gram negative bacteria, wherein the alkyl polyethoxy carboxylate is of the formula RO(CH2CH2O)kCH2COO−M+; wherein R is a C8-C22 alkyl; wherein k is an integer from 0 to 20; and wherein M is a soluble salt-forming cation; and wherein the alkyl polyethoxy amides are of the formula RO(CH2CH2O)kCH2CONH2 wherein R is a C8-C22 alkyl, and k is an integer from 0 to 20. ### Claim 2 (depends on 1) The composition according to claim 1, wherein the alkyl polyethoxy carboxylate is present in an amount of about 4.8 wt %. ### Claim 3 (depends on 2) The composition according to claim 2, wherein in the alkyl polyethoxy carboxylate, R is a C12 alkyl, K is 11, and M is Na. ### Claim 4 (depends on 1) The composition according to claim 1, wherein the betaine surfactant is present in an amount of about 1.3 wt %. ### Claim 5 (depends on 1) The composition according to claim 1, wherein the betaine comprises cocoamidopropyl betaine. ### Claim 6 (depends on 1) The composition according to claim 1, wherein the alkyl polyethoxy amide comprises PEG 4 rapeseed amide. ### Claim 7 (depends on 1) The composition according to claim 1, wherein the metal salt is present in an amount of from 0.1-5 wt %. ### Claim 8 (depends on 1) The composition according to claim 1, wherein the metal salt comprises one or both of an alkali and an alkaline metal halide. ### Claim 9 (depends on 1) The composition according to claim 1, wherein the alkyl ether sulphate comprises sodium laureth sulphate. ### Claim 10 (depends on 1) A method for providing a germicidal benefit to a topical surface comprising: contacting a topical surface with the composition according to claim 1; and providing an effective germicidal benefit against fungi, gram-positive and gram-negative bacteria if the topical surface, prior to contact with the composition, had the presence of one or more of fungi, gram-positive and gram-negative bacteria. ### Claim 11 (depends on 1) A method for providing a germicidal benefit to a dermal surface comprising: contacting a dermal surface with the composition according to claim 1; and providing an effective germicidal benefit against undesired pathogens if the dermal surface, prior to contact with the composition, had the presence of one or more undesired pathogens, while not upsetting or disrupting the natural balance of microflora or microbiome on the dermal surface. ### Claim 12 (depends on 1) A method for stabilizing the pH of a surface comprising contacting a surface upon which the presence of one or more undesired pathogens are known or suspected, with the composition according to claim 1. ### Claim 13 (depends on 1) A method for stabilizing microbiome or microflora of a surface comprising contacting a surface upon which the presence of one or more undesired pathogens are known or suspected, with the composition according to claim 1. ### Claim 14 (depends on 1) A method of moisturizing a surface comprising contacting a surface upon which the presence of one or more undesired pathogens are known or suspected, with the composition according to claim 1. ### Claim 15 A personal wash composition comprising: sodium laureth carboxylate in an amount of about 4.8 wt %; betaine surfactant in an amount of about 1.3 wt %; lactic acid in an amount of about 2 wt % to 5 wt % wt %; glycerol in an amount of from 10-15 wt %; rapeseed amide in an amount of from 1-3 wt %; sodium laureth sulfate in an amount of greater than 8 wt %; 10-20 wt % total surfactant; and sodium chloride in an amount of about 2 wt %, wherein the composition has a pH of 4 to 4.4. ### Claim 16 (depends on 1) The composition according to claim 1, wherein the composition has a pH of 4 to 4.4.