# US 11,896,625 B2 · Method for producing therapeutic agent for skin lesions, and therapeutic agent for skin lesions

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- Number: US 11,896,625 B2
- Document ID: US11896625B2
- Status: Granted
- Kind: B2
- Application number: 17/480,327
- Filed: 2021-09-21
- Published: 2022-01-06
- Granted: 2024-02-13
- Earliest claimed: 2017-03-21
- Assignees: Well Stone Co.
- Applicants: Well Stone Co.
- Inventors: Yoichi Ishii; Takeshi Okamoto; Sayaka Makino
- Web page: https://patentgrep.com/patent/US11896625B2

## CPC

- A61K 35/62: Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 9/08: Solutions {(composition of solutions A61K47/00)}
- A61K 9/12: Aerosols; Foams {(A61K9/0043, A61K9/0056, A61K9/006, A61K9/0073 take precedence; spray-films A61K9/7015)}
- A61K 35/02: from inanimate materials (carbon A61K33/44)
- A61K 36/13: Coniferophyta (gymnosperms)
- A61P 17/02: for treating wounds, ulcers, burns, scars, keloids, or the like
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

Provided are: a method of producing a therapeutic agent for skin lesions suitable for treatment or prevention of a skin lesion such as a bedsore; and a therapeutic agent for skin lesions produced by the production method. The method of producing a therapeutic agent for skin lesions characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the therapeutic agent for skin lesions produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.

## Claims

### Claim 1

A method of producing a therapeutic agent for skin lesions comprising the steps of:
(a) mixing earthworm castings with water to obtain a mixture while warming at 30 to 50° C.;
(b) vaporizing the mixture to generate a vaporized water; and
(c) collecting the vaporized water generated from the mixture to obtain a liquid containing the therapeutic agent.

### Claim 2 (depends on 1)

The method according to claim 1, further comprising mixing an organic substance together with the earthworm castings and the water in the mixing step.

### Claim 3 (depends on 2)

The method according to claim 2, wherein the organic substance is a wood material.

### Claim 4 (depends on 1)

The method according to claim 1, further comprising a diluting step of diluting the liquid obtained in the collecting step with water.
