Compositions for therapy and health containing amino acids with bitter taste
AssigneeAxcella (Assignment for the Benefit of Creditors), LLC
InventorsThomas Hanlon, Andrew M. Wood
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Abstract
This disclosure provides a dry powder formulation of free amino acids with an acceptable and even good taste profile.
Claims33
A dry blended preparation comprising at least three amino acids entities and an excipient formulation, wherein the dry blended preparation is suitable for oral administration, wherein at least one amino acid entity has a bitter taste and the dry blended preparation has an acceptable taste, wherein the excipient formulation has fewer than eleven (11) ingredients, wherein the amino acid entities are not part of a peptide longer than 20 amino acids long, wherein the bitter tasting amino acid is arginine, valine, leucine, isoleucine, tryptophan, or phenylalanine;
- and one or both of:
- the excipient formulation comprises acesulfame, and acesulfame is present in the dry blended preparation at a level less than 1% (w/w);
- or
- the excipient formulation comprises sucralose, and sucralose is present in the dry blended preparation at a level less than 1.0% (w/w).
Dependencies are inferred from the claim text.