US 11,894,121 B2 · Prescriptive nutrition-based IV and IM infusion treatment formula creation systems and methods

Abstract

A method of creating a genetically personalized intravenous or intramuscular nutrition therapy treatment formula includes developing an initial mapping of individual micronutrients to SNPs, symptoms, conditions, and therapeutic objectives based on existing individual scientific literature references that link the specific micronutrient to an SNP, a symptom, a condition, or a therapeutic objective. The method includes receiving an SNP and a symptom, a condition, or a therapeutic objective for a patient, comparing the SNP, symptom, condition, therapeutic objective combination with the initial mapping to identify matching micronutrients, creating a custom treatment formula with the identified micronutrients, and treating the patient with the formula. Feedback data about the formula's effectiveness is received and the initial mapping is updated to account for the feedback data. This process is repeated for subsequent patients positioned geographically remotely from each other so that future patients are treated with reference to an updated current mapping.

A method of creating a genetically personalized intravenous or intramuscular nutrition therapy treatment formula, the method comprising:

developing an initial mapping of each of a plurality of individual micronutrients to a single nucleotide polymorphism (SNP) and to at least one of a symptom, a condition, and a therapeutic objective, the developing the initial mapping comprising, for each specific micronutrient of the plurality of individual micronutrients:
(1) assigning an individual score to each of a plurality of existing individual scientific literature references that links the specific micronutrient to an SNP, a symptom, a condition, or a therapeutic objective, wherein a value of the individual score is weighted based on one or more factors;
(2) adding the individual scores for each of the plurality of existing individual scientific literature references for the specific micronutrient with respect to each combination of an SNP and at least one of a symptom, a condition, and a therapeutic objective;
and
(3) determining that the specific micronutrient matches the SNP and the at least one of a symptom, a condition, and a therapeutic objective when the individual scores for the specific micronutrient with respect to the SNP and the at least one of a symptom, a condition, and a therapeutic objective add up to more than a predetermined threshold;
storing the initial mapping, the individual scores, and the added scores in a database;
receiving an SNP for a first patient and at least one of a symptom, a condition, and a therapeutic objective for the first patient;
comparing the SNP for the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient with the initial mapping stored in the database to identify one or more micronutrients that have been matched to the SNP for the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
creating a custom intravenous or intramuscular nutrition therapy treatment formula for the first patient, wherein the identified one or more micronutrients are ingredients of the custom intravenous or intramuscular nutrition therapy treatment formula, and wherein a dosage of each of the identified one or more micronutrients is selected based on the SNP of the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
treating the first patient with the custom intravenous or intramuscular nutrition therapy treatment formula;
receiving feedback data about an effectiveness of the custom intravenous or intramuscular nutrition therapy treatment formula in addressing the at least one of a symptom, a condition and a therapeutic objective for the first patient;
assigning an individual treatment score for the identified one or more micronutrients in the custom intravenous or intramuscular nutrition therapy treatment formula with respect to the SNP for the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient based on the feedback data, wherein a value of the individual treatment score is weighted based on one or more factors, wherein the individual treatment score is positive when the feedback data shows improvement of the at least one of a symptom, a condition, and a therapeutic objective for the first patient, and wherein the individual treatment score is negative when the feedback data shows worsening of the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
updating the initial mapping by:
(1) adding the individual treatment score for the identified one or more micronutrients in the custom intravenous or intramuscular nutrition therapy treatment formula to the added scores stored in the database that are associated with the identified one or more micronutrients, the SNP for the first patient, and the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
(2) comparing the updated added scores with the predetermined threshold to reevaluate whether there are matches for the identified one or more micronutrients in the custom intravenous or intramuscular nutrition therapy treatment formula;
and
(3) storing the updated initial mapping, the individual treatment score, and the updated added scores in the database;
and
for each of a plurality of subsequent patients positioned geographically remotely from each other:
receiving an SNP of the subsequent patient and at least one of a symptom, a condition, and a therapeutic objective of the subsequent patient;
comparing the SNP for the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient with a current mapping stored in the database to identify one or more micronutrients that have been matched to the SNP for the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient, wherein the current mapping has been updated with the individual treatment score of the first patient and individual treatment scores of any other previously treated patient;
creating a custom intravenous or intramuscular nutrition therapy treatment formula for the subsequent patient, wherein the identified one or more micronutrients are ingredients of the custom intravenous or intramuscular nutrition therapy treatment formula, and wherein a dosage of each of the identified one or more micronutrients is selected based on the SNP of the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient;
treating the subsequent patient with the custom intravenous or intramuscular nutrition therapy treatment formula;
receiving feedback data about an effectiveness of the custom intravenous or intramuscular nutrition therapy treatment formula in addressing the at least one of a symptom, a condition and a therapeutic objective for the subsequent patient;
assigning an individual treatment score for the identified one or more micronutrients in the custom intravenous or intramuscular nutrition therapy treatment formula with respect to the SNP for the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient based on the feedback data, wherein a value of the individual treatment score is weighted based on one or more factors, wherein the individual treatment score is positive when the feedback data shows improvement of the at least one of a symptom, a condition, and a therapeutic objective for the first patient, and wherein the individual treatment score is negative when the feedback data shows worsening of the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
updating the current mapping by:
(1) adding the individual treatment score for the identified one or more micronutrients in the custom intravenous or intramuscular nutrition therapy treatment formula for the subsequent patient to current added scores stored in the database that are associated with the identified one or more micronutrients, the SNP for the subsequent patient, and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient;
(2) comparing the updated current added scores with the predetermined threshold to reevaluate whether there are matches for the identified one or more micronutrients in the custom intravenous or intramuscular nutrition therapy treatment formula for the subsequent patient;
and
(3) storing the updated current mapping, the individual treatment score of the subsequent patient, and the updated current scores in the database;
and
treating future patients with reference to the updated current mapping.

29 more elements

Prescriptive nutrition-based IV and IM infusion treatment formula creation systems and methods

Life of this patent

Prescriptive nutrition-based IV and IM infusion treatment formula creation systems and methods

Life of this patent

Abstract

Claims20