Systems and methods improving optical coherence tomography (OCT) image resolution using k-linearization (KL) and dispersion correction (DC)
AssigneeLightLab Imaging, Inc.
InventorsChih-Hao Liu, Steven M. Stromski
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Abstract
Aspects of the disclosure relate to systems, methods, and algorithms to perform wavenumber linearization and dispersion correction in optical systems without the need for hardware modifications, empirical adjustments, precise mirror alignment, and which can be conducted at low computational costs and in real-time. A one-time calibration process can generate spectra or calibration criteria, including wavenumber-linearization criteria, dispersion correction, and spectral flattening spectra, which can be used to correct an optical coherence tomogram in real time.
Claims18
A method of processing an optical signal, the method comprising:
- calibrating an optical system, the calibration comprising:
- acquiring, by one or more processors, at least a first mirror measurement and a second mirror measurement, the first and second mirror measurement being collected from either side of a zero-delay line;
- obtaining, by the one or more processors, an amplitude and phase for the first mirror measurement and the second mirror measurement;
- resampling, at least one of the first mirror measurement and the second mirror measurement to be at least one of:
- (i) in linear wavenumber (k) space or (ii) linear wavelength or (iii) linear time, to generate a resampled mirror measurement;
- performing spectral flattening on at least one mirror measurement by using an envelope calculated from a specific mirror measurement;
- and
- calculating, using a function, an optimized fit for the resampled mirror measurement.
A system, comprising:
- a memory for storing image data and time-varying data that corresponds to a subject;
- and one or more processors in communication with the memory, the one or more processors being operable to:
- acquire, by one or more processors, at least a first mirror measurement and a second mirror measurement, the first and second mirror measurement being collected from either side of a zero-delay line, each mirror measurement being an interferogram or a signal or a system impulse response;
- compute, by the one or more processors, an amplitude and phase for the first mirror measurement and the second mirror measurement;
- resample, at least one of the first mirror measurement and the second mirror measurement to be at least one of:
- (i) in linear wavenumber(k) space, (ii) linear wavelength, or (iii) linear time to generate a resampled mirror measurement;
- perform spectral flattening on at least one mirror measurement by using an envelope calculated from a specific mirror measurement;
- and
- calculate, using a function, an optimized fit for the resampled mirror measurement.
A non-transitory computer readable medium containing instructions executable by one or more processors to perform a method, comprising:
- acquiring at least a first mirror measurement and a second mirror measurement, the first and second mirror measurement being collected from either side of a zero-delay line, each mirror measurement being an interferogram or a signal or a system impulse response;
- computing amplitude and phase for the first mirror measurement and the second mirror measurement;
- resampling, at least one of the first mirror measurement and the second mirror measurement to be at least one of:
- (i) in linear wavenumber(k) space, (ii) linear wavelength, or (iii) linear time to generate a resampled mirror measurement;
- performing spectral flattening on at least one mirror measurement by using an envelope calculated from a specific mirror measurement;
- and
- calculate, using a function, an optimized fit for the resampled mirror measurement.
Dependencies are inferred from the claim text.