Method for biomimetic culture of urothelial cells and uses thereof
AssigneeChina Medical University
InventorsChih-Rong Shyr, Chi-Ping Huang, Chun-Chie Wu
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Abstract
The invention discloses a methodology for the biomimetic culture of urothelial cells from mammalian bladders, including murine, porcine, bovine and human sources to isolate and expand urothelial cells for use in various applications, such as intravesical urothelial cell therapy to treat cystitis and bladder cancer.
Claims5
A method for treating a subject suffering from urothelial carcinoma, or bladder cancer, comprising administering intravesically to the subject an effective amount of a composition comprising xenogeneic urothelial cells in a solution wherein the xenogeneic urothelial cells are urothelial stem cells, urothelial progenitor cells, urothelial precursor cells and mature urothelial cells.
Dependencies are inferred from the claim text.