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US 11,891,432 B2Granted
Anti-dengue virus antibodies having cross-reactivity to Zika virus and methods of use
AssigneesChugai Seiyaku Kabushiki Kaisha, Agency for Science, Technology and Research
InventorsKatja Fink, Cheng-I Wang, Lisa Fong Poh Ng, Laurent Renia, Zenjiro Sampei, Xing'er Christine Xoo
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Abstract
The disclosure provides anti-DENV antibodies having a cross-reactivity to ZIKV and methods of making and using the same. The anti-DENV antibodies have uses that include treating or preventing ZIKV infection.
Claims2
A method for treating Zika virus infection, comprising administering an antibody that binds to Zika virus, wherein the antibody comprises:
- a VH comprising the amino acid sequence of SEQ ID NO:
- 6,
- a human IgG1 CH comprising the amino acid sequence of SEQ ID NO:
- 59,
- a VL comprising the amino acid sequence of SEQ ID NO:
- 7, and
- a human CL.
4 more elements
Dependencies are inferred from the claim text.