Back to results
US 11,891,421 B2Granted
Variant of a BPIFB4 protein
AssigneeLgvi S.R.L.
InventorsAnnibale Alessandro Puca, Carmine Vecchione
Life of this patent
Estimating the term…
Abstract
The present invention relates to a variant of BPIFB4 protein (Bactericidal/Permeability Increasing protein family B, member 4) and to a polynucleotide or a vector encoding said variant of BPIFB4 protein and to their use for the treatment of pathologies involving impairment of nitric oxide signalling.
Claims13
An isolated polynucleotide encoding a BPIFB4 protein variant consisting of the amino acid sequence of SEQ ID NO:
- 1, said protein variant having activity in increasing the activity of eNOS and/or the production of NO.
Dependencies are inferred from the claim text.