US 11,891,409 B2 · Trifluoromethyl alkenylphosphonate and preparation method therefor

Abstract

Disclosed are a trifluoromethyl alkenylphosphonate derivative and preparation method therefor. The preparation method comprises the following steps: dissolving an acetylene derivative, an iodine compound, and a phosphorus reagent in a solvent for reaction at the temperature from the room temperature to 100° C. to obtain the trifluoromethyl alkenylphosphonate derivative. In the present invention, the acetylene derivative is used as a starting material, and the raw materials are easily available and diversified; products obtained by using the method of the present invention have various types and can be directly used and also used for other further reactions; moreover, the method disclosed in the present invention has the advantages of short steps, mild reaction conditions, simple reaction operation and post-treatment processes, and high yield, and is suitable for large-scale production.

Claims6

Dependent claims

A method for preparing a trifluoromethyl alkenylphosphonate derivative comprising:

reacting an acetylene derivative, an iodine compound, and a phosphorus reagent in a solvent at room temperature to obtain the trifluoromethyl alkenylphosphonate derivative,
wherein:
the acetylene derivative has the following structure:
the iodine compound has the following structure:
the phosphorus reagent has the following structure:
P(OR4)3;
the trifluoromethyl alkenylphosphonate derivative has the following structure:
R1 is aryl, cyano, or ester;
R2 is hydrogen, cyano or ester;
and R4 is methyl, ethyl, isopropyl or butyl.

7 more elements

Dependencies are inferred from the claim text.

Trifluoromethyl alkenylphosphonate and preparation method therefor

Life of this patent

Trifluoromethyl alkenylphosphonate and preparation method therefor

Life of this patent

Abstract

Claims6