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US 11,890,620 B2Granted
Miniaturized DNA microarray for small-volume sample processing
AssigneeThe Charles Stark Draper Laboratory, Inc.
InventorsKirsty A. McFarland, Charles A. Lissandrello, Andrew P. Magyar, Erin Rosenberger
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Abstract
Miniaturized DNA microarrays are described to be used in conjunction with microfluidic channels or microcentrifuge tubes and microcentrifuge filters to reduce sample size, incubation time and to increase overall binding efficiency.
Claims7
A miniaturized DNA microarray assembly, consisting of:
- a) a single high-density array of oligonucleotide probes printed on a single solid substrate, wherein the dimensions of the solid substrate are about 14.0 mm by about 8 mm, or less;
- b) an inert enclosure surrounding sides and bottom of the single solid substrate, wherein the enclosure has a fluid inlet port and a fluid outlet/exit port which allows fluid to flow over and contact the oligonucleotide probes of the array;
- and
- c) an optically transparent top surface sealed to the enclosure.
1 more element
Dependencies are inferred from the claim text.