System and method of pain relief based on frequency based analysis of temporal nociceptive signals
AssigneeLumbrera LLC
InventorsRicardo Vallejo, David Leonardo Cedeno, William J. Smith
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Abstract
An apparatus, system and technique selectively eliminates the noxious signal components in a neuronal signal by creating an interfering electrical signal that is tuned to a given frequency corresponding to the oscillatory pattern of the noxious signal, resulting in a modified neuronal signal that substantially reproduces a normal, no-pain neuronal signal. The disclosed system and technique of pain relief is based on the hypothesis that the temporal profile of pain signals encodes particular components that oscillate at unique and quantifiable frequencies, which are responsible for pain processing in the brain.
Claims20
An electromagnetic stimulation system comprising:
- a non-transitory memory for storing a plurality of modulation signal parameter programs;
- a selection device for selecting one of the plurality of modulation signal parameter programs,
- a signal generator responsive to a selected of the plurality of modulation signal parameter programs and configured to generate a correction signal;
- and
- an output for connection to at least one electrode operatively coupled to the signal generator and configured for delivering the correction signal to an application point in an afferent pathway of a mammalian subject;
- wherein the correction signal in combination with a nociceptive signal in the afferent pathway distal of the application point has a temporal profile which is different from a temporal profile of a nociceptive signal proximal of the application point.
A method for neutralizing components in a signal in a neurological pathway of a mammalian subject, the method comprising:
- A) acquiring a signal at a sensing point in the neurological pathway of the subject, the signal acquired having a temporal profile characteristic of an afferent signal in the neurological pathway;
- B) identifying a characteristic in a frequency based power analysis of the signal acquired;
- and
- C) generating a correction signal which when applied to the neurological pathway proximate the sensing point combines with the afferent signal resulting in a modified afferent signal distal of the sensing point which is absent the identified characteristic.
A system for neutralizing components in a signal in a neurological pathway of a mammalian subject, the system comprising a processor and a non-transitory computer-readable storage medium storing instruction that, when executed by the processor, cause the processor to perform a method, the method comprising:
- A) acquiring a signal at a sensing point in the neurological pathway of the subject, the signal acquired having a temporal profile characteristic of an afferent signal in the neurological pathway;
- B) identifying a characteristic in a frequency based power analysis of the signal acquired;
- and
- C) generating a correction signal which when combined with the afferent signal in the neurological pathway results in a modified afferent signal absent the identified characteristic.
Dependencies are inferred from the claim text.