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US 11,890,349 B2Granted
Treatment of inflammatory diseases with inhibitors of C5A activity
AssigneeInflaRx GmbH
InventorsRenfeng Guo, Niels C. Riedemann
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Abstract
The present invention relates to inhibitors of C5a activity and their use in the treatment of cutaneous, neutrophilic, inflammatory diseases in a subject.
Claims2
A method of treating hidradenitis suppurativa (HS) or an HS-related disorder;
- the method comprising:
- administering to a subject in need thereof an effective amount of a selective C5a receptor inhibitor, wherein the inhibitor is avacopan having the formula:
- wherein the HS-related disorder is selected from Pyoderma gangrenosum (PG);
- PASH (PG, acne and hidradenitis suppurativa) and PAPASH (pyogenic arthritis, acne, PG and hidradenitis suppurativa).
1 more element
Dependencies are inferred from the claim text.