Endolysins active against Bacillus bacteria, pharmaceutical compositions, and methods relating thereto
AssigneesUniversity of Maryland, College Park, The United States of America as represented by the Secretary of the Navy
InventorsDaniel C. Nelson, Irina V. Etobayeva
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Abstract
The present invention relates to methods of treating or preventing a bacterial disease or infection, antibacterial compositions, and antibacterial surfaces, including an isolated polypeptide comprising an enzymatically active domain (EAD) of a Bacillus bacteriophage endolysin.
Claims5
A method of treating a bacterial infection in a subject comprising administering to said subject a therapeutically effective amount of an isolated polypeptide comprising an amino acid sequence of SEQ ID NO:3, or variants thereof have at least about 90% identity thereto.
Dependencies are inferred from the claim text.