# US 11,890,313 B2 · Natural drugs for the treatment of inflammation and melanoma

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- Number: US 11,890,313 B2
- Document ID: US11890313B2
- Status: Granted
- Kind: B2
- Application number: 17/929,434
- Filed: 2022-09-02
- Published: 2022-12-29
- Granted: 2024-02-06
- Earliest claimed: 2016-12-16
- Assignees: Herbalife International, Inc.
- Applicants: Herbalife International, Inc
- Inventors: Bruce L. Howe
- Web page: https://patentgrep.com/patent/US11890313B2

## CPC

- A61K 36/9068: Zingiber, e.g. garden ginger
- A61K 9/127: Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K 9/14: Particulate form, e.g. powders, {Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles (microspheres A61K9/16; microcapsules A61K9/50; nanocapsules, nanoparticles of the matrix type A61K9/51)}
- A61K 31/12: Ketones
- A61K 31/56: Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K 31/685: one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
- A61K 36/324: Boswellia, e.g. frankincense
- A61K 36/9066: Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)

## Abstract

The invention is directed to natural drug compositions comprising turmeric, boswellia and ginger. Methods for the use of the inventive drug compositions in the treatment of inflammatory disorders and melanoma are within the scope of the invention.

## Claims

### Claim 1

A method for treating inflammation in a human, the inflammation due to a disorder selected from the group consisting of Type II diabetes, inflammatory bowel disease, and rheumatoid arthritis, the method comprising:
identifying a human having inflammation due to a disorder in the human, wherein the disorder is selected from the group consisting of Type II diabetes, inflammatory bowel disease, and rheumatoid arthritis; and
administering to the human a composition comprising about 50% turmeric extract, about 30% Boswellia extract, and about 20% ginger extract.

### Claim 2 (depends on 1)

The method of claim 1, wherein the turmeric extract is standardized to about 95% curcuminoids.

### Claim 3 (depends on 2)

The method of claim 2, wherein the turmeric extract comprises about 1% lecithin and about 1% turmeric oil.

### Claim 4 (depends on 1)

The method of claim 1, wherein the boswellia extract is standardized to about 30% boswellic acid.

### Claim 5 (depends on 4)

The method of claim 4, wherein the boswellic acid comprises acetyl-11-keto-beta-boswellic acid.

### Claim 6 (depends on 4)

The method of claim 4, wherein the boswellia extract comprises about 1% lecithin and about 1% boswellia oil.

### Claim 7 (depends on 1)

The method of claim 1, wherein the ginger extract is standardized to about 20% gingerols.

### Claim 8 (depends on 7)

The method of claim 7, wherein the ginger extract comprises about 1% lecithin and about 1% ginger oil.

### Claim 9 (depends on 8)

The method of claim 8, wherein the composition is encapsulated within a liposome.

### Claim 10 (depends on 1)

The method of claim 1, wherein the disorder is Type II diabetes.

### Claim 11 (depends on 1)

The method of claim 1, wherein the disorder is inflammatory bowel disease.

### Claim 12 (depends on 1)

The method of claim 1, wherein the disorder is rheumatoid arthritis.