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US 11,890,286 B2Granted
Methods and compositions for treating cancer
AssigneeThe University of Chicago
InventorsAli Ekram Yesilkanal, Marsha Rosner
Life of this patent
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Abstract
Methods and compositions for treating cancer are disclosed.
Claims7
A method for treating a patient with cancer, comprising:
- (a) obtaining a cancer sample of a primary cancer from the patient;
- (b) measuring expression levels of ROCK2, DOCK4, ITGA1, APC, and RAPGEF2 in the cancer sample;
- and
- (c) administering a therapeutically effective amount of a composition comprising a MEK inhibitor, a p38MAPK inhibitor, a JNK inhibitor, and a MLK inhibitor to the patient when the expression levels of ROCK2, DOCK4, ITGA1, APC, and RAPGEF2 in the cancer sample are increased relative to the expression levels of the same genes in a control sample.
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Dependencies are inferred from the claim text.