Method and device for detecting a neural response in a neural measurement
AssigneeSaluda Medical Pty Ltd
InventorsPeter Scott Vallack Single, Dean Michael Karantonis
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Abstract
A method for processing a neural measurement obtained in the presence of artifact, in order to detect whether a neural response is present in the neural measurement. A neural measurement is obtained from one or more sense electrodes. The neural measurement is correlated against a filter template, the filter template comprising at least three half cycles of an alternating waveform, amplitude modulated by a window. From an output of the correlating, it is determined whether a neural response is present in the neural measurement.
Claims43
A controller for an implantable device, the controller comprising a processor configured to:
- control an electrical stimulus source to generate a first electrical stimulus to be applied to neural tissue, the first electrical stimulus defined by at least one stimulus parameter;
- obtain a neural measurement from one or more sense electrodes, the neural measurement comprising an artefact;
- and
- correlate the neural measurement against a filter template configured to detect a neural response evoked by the first electrical stimulus generated by the electrical stimulus source to determine a correlation;
- determine a magnitude of the neural response evoked by the first electrical stimulus based on the correlation;
- and
- use the magnitude of the neural response in a closed loop feedback circuit to determine the at least one stimulus parameter to control neuromodulation.
A method of controlling a neural stimulus, the method comprising:
- generating a first electrical stimulus to be applied to neural tissue, the first electrical stimulus defined by at least one stimulus parameter;
- obtaining a neural measurement from one or more sense electrodes, the neural measurement comprising an artefact;
- correlating the neural measurement against a filter template configured to detect a neural response evoked by the first electrical stimulus to determine a correlation;
- determining a magnitude of the neural response evoked by the first electrical stimulus based on the correlation;
- and
- using the magnitude of the neural response in a closed loop feedback circuit to determine the at least one stimulus parameter to control neuromodulation.
A non-transitory computer readable medium comprising machine-readable instructions, which when executed by a processor cause the processor to:
- control an electrical stimulus source to generate a first electrical stimulus to be applied to neural tissue, the first electrical stimulus defined by at least one stimulus parameter;
- obtain a neural measurement from one or more sense electrodes, the neural measurement comprising an artefact;
- correlate the neural measurement against a filter template configured to detect a neural response evoked by the first electrical stimulus generated by the electrical stimulus source to determine a correlation;
- determine a magnitude of the neural response evoked by the first electrical stimulus based on the correlation;
- and
- use the magnitude of the neural response in a closed loop feedback circuit to determine the at least one stimulus parameter to control neuromodulation.
Dependencies are inferred from the claim text.