Compute system with psoriasis diagnostic mechanism and method of operation thereof

A compute system comprising:

• a control circuit, including a processor, configured to:
• generate a skin segmentation including a non-skin region and a skin prediction based on a patient image,
• generate a body part segmentation based on the patient image,
• generate a cropped image based on the skin segmentation and the body part segmentation with the cropped image includes the non-skin region based on the skin prediction,
• generate a psoriasis segmentation based on the cropped image and the skin prediction,
• generate intermediate scores for erythema, induration, and desquamation for the cropped image, and
• generate a full body PASI score based on the psoriasis segmentation and the intermediate scores for displaying on a device to assist in diagnosis.

A non-transitory computer readable medium including instructions for a compute system comprising:

• generating a skin segmentation including a non-skin region and a skin prediction based on a patient image;
• generating a body part segmentation based on the patient image;
• generating a cropped image based on the skin segmentation and the body part segmentation with the cropped image including the non-skin region based on the skin prediction;
• generating a psoriasis segmentation based on the cropped image and the skin prediction;
• generating intermediate scores for erythema, induration, and desquamation for the cropped image;
• and
• generating a full body PASI score based on the psoriasis segmentation and the intermediate scores for displaying on a device to assist in diagnosis.