Mammalian cell cryopreservation liquid
AssigneeOtsuka Pharmaceutical Factory, Inc.
InventorsMasuhiro Nishimura, Natsuki Watanabe, Yasutaka Fujita, Tamaki Wada
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Abstract
A liquid for cryopreserving a cell and a liquid for administration of a mammalian cell capable of cryopreserving a mammalian cell and effectively suppressing cell death after thawing, and a method for cryopreserving a mammalian cell using the cell cryopreservation liquid. The liquid is an isotonic solution that includes 2.0 to 6.0% (w/v) of trehalose or a derivative thereof, or a salt of the trehalose or the derivative, 4.0 to 7.0% (w/v) of dextran or a derivative thereof, or a salt of the dextran or the derivative, and DMSO or glycerin.
Claims7
A liquid for cryopreserving a mammalian cell, consisting of an isotonic solution comprising:
- 2.0 to 6.0% (w/v) of trehalose or a trehalose derivative, or a salt of the trehalose or the trehalose derivative, 4.0 to 7.0% (w/v) of dextran or a dextran derivative, or a salt of the dextran or the dextran derivative, and 2.0 to 15% (v/v) of dimethylsulfoxide or glycerin, and not containing any of serum, albumin or glucose.
Dependencies are inferred from the claim text.