Automated ion optics charging compensation

A mass spectrometer, comprising:

• at least one ion source for generating ions,
• an ion guide for collisionally cooling said ions,
• at least one mass analyzer positioned downstream of said ion guide for performing mass analysis on said collisionally cooled ions,
• at least one lens element located between the ion guide and the mass analyzer,
• at least one DC voltage source for applying a DC voltage to said lens element,
• a controller in communication with said voltage source for ramping a DC voltage applied to said lens element,
• a detector positioned downstream of said mass analyzer for detecting ions passing through said mass analyzer and generating mass detection signals as the DC voltage is ramped,
• an analyzer in communication with said detector for receiving said mass detection signals from said detector and generating a mass ion signal, said analyzer being configured to extract one or more characteristics of any of said mass ion signal and said voltage ramp,
• said analyzer being in communication with said controller to provide control signals thereto for adjusting a DC voltage applied to said lens element based on said one or more characteristics of the ion signal and the voltage ramp.