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US 11,887,745 B2Granted
Methods for producing radionuclides using minimal targeting material
AssigneeWashington University
InventorGregory Gaehle
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Abstract
Among the various aspects of the present disclosure is the provision of methods for producing radioisotopes and improving the specific activity of radioisotopes (e.g., Cu-64 chloride). As described herein, the method includes matching of the target material and the proton beam strike area, resulting in improved specific activity while reducing the amount of target material used.
Claims18
A method for manufacturing a radioisotope with improved specific activity comprising:
- providing a target material comprising a Ni isotope;
- providing a target material holder;
- providing a proton beam comprising a proton beam energy and a proton beam strike area;
- providing a material holder mounting flange capable of measuring a proton beam current of the target material for beam steering;
- and
- introducing the proton beam to the target material, resulting in a composition comprising a Cu radioisotope;
- wherein,
- the target material comprises a target material area;
- and
- the target material area matches the proton beam strike area, resulting in matching of the target material and the proton beam.
7 more elements
Dependencies are inferred from the claim text.