Quality control for point-of-care diagnostic systems

A system for point-of-care medical diagnostics, the system comprising:

• a flow cytometry hematology analyzer configured to analyze subject samples and to analyze a consumable synthetic quality control material, the flow cytometry analyzer comprising one or more subsystems, wherein the flow cytometry hematology analyzer is structurally configured to be in communication with a storage container storing a consumable synthetic quality control material, the synthetic quality control material structurally configured to be stored at room temperature;
• a database configured to store quality control results over time, the quality control results over time including results of the flow cytometry hematology analyzer analyzing the consumable synthetic quality control material over time;
• one or more processors;
• and
• at least one memory storing instructions, which, when executed by the one or more processors, cause the system to:
• (a) perform quality control procedures by accessing the consumable synthetic quality control material from the storage container;
• (b) analyze the consumable synthetic quality control material using the flow cytometry hematology analyzer;
• (c) generate quality control results;
• (d) store the generated quality control results in the database;
• (e) repeat steps (a)-(d) over time;
• (f) generate control parameters based on the generated quality control results stored in the database;
• (g) determine whether a parameter of the control parameters is out-of-tolerance based on the quality control results;
• and
• (h) in response to determining that the parameter of the control parameters is out- of-tolerance, adjust at least one sub-system of the one or more sub-systems without user intervention to bring the out-of-tolerance parameter within tolerance.