Systems and methods to process electronic images to produce a tissue map visualization

A system for analyzing an image of a slide corresponding to a pathology specimen, the system comprising:

• at least one memory storing instructions;
• and
• at least one processor configured to execute the instructions to perform operations comprising:
• determining, using an artificial intelligence (AI) system, a salient region overlay for at least one digitized image of the pathology specimen;
• representing the salient region overlay by a set of super-pixels associated with a score;
• suppressing, based on a diagnostic value for each pixel, one or more non-salient regions of the at least one digitized image;
• and
• normalizing the salient region overlay to obtain a variable, the salient region overlay represented by a binary segmentation of the at least one digitized image indicating if each pixel has a salient feature present.

A computer-implemented method for analyzing an image of a slide corresponding to a pathology specimen, the method comprising:

• determining, using an artificial intelligence (AI) system, a salient region overlay for at least one digitized image of the pathology specimen;
• suppressing, based on a diagnostic value for each pixel, one or more non-salient regions of the at least one digitized image;
• normalizing the salient region overlay to obtain a variable, the salient region overlay represented by a binary segmentation of the at least one digitized image indicating if each pixel has a salient feature present;
• and
• representing the salient region overlay by a semantic segmentation of the at least one digitized image indicating a score or probability for each pixel.

A system for analyzing an image of a slide corresponding to a pathology specimen, the system comprising:

• at least one memory storing instructions;
• and
• at least one processor configured to execute the instructions to perform operations comprising:
• determining, using an artificial intelligence (AI) system, a salient region overlay for at least one digitized image of the pathology specimen;
• suppressing, based on a diagnostic value for each pixel, one or more non-salient regions of the at least one digitized image;
• normalizing the salient region overlay to obtain a variable, the salient region overlay represented by a binary segmentation of the at least one digitized image indicating if each pixel has a salient feature present;
• and
• representing the salient region overlay by a semantic segmentation of the at least one digitized image indicating a score or probability for each pixel.