Chromatography analysis system

A chromatography analysis system comprising:

• a liquid delivery pump configured to deliver a mobile phase;
• an autosampler fluidly connected downstream of the liquid delivery pump and configured to inject a sample into the mobile phase delivered by the liquid delivery pump;
• a separation column that is fluidly connected downstream of the autosampler and configured to separate a sample into components;
• a column oven having an internal space accommodating the separation column, a heater for heating inside of the internal space, and a temperature sensor configured to detect a temperature of the internal space, the column oven having a temperature control function of controlling a temperature of the separation column at a temperature higher than room temperature;
• a detector configured to detect the components in eluate from the separation column;
• a shutdown execution part configured to start shutdown to finally stop driving of the liquid delivery pump and temperature control operation of the column oven at a time when a predetermined situation occurs, by controlling operation of the liquid delivery pump and the column oven;
• and
• a column protection temperature setter configured to set a column protection temperature for preventing deterioration of the separation column due to overheating,
• wherein the shutdown execution part is configured to stop driving of the heater of the column oven in a state where the liquid delivery pump is driven when the shutdown is started, and then, stop driving of the liquid delivery pump after a temperature of the internal space detected by the temperature sensor becomes equal to or less than the column protection temperature, and
• wherein the column protection temperature setter is configured to set a temperature that is input by a user as the column protection temperature.

A chromatography analysis system comprising:

• a liquid delivery pump configured to deliver a mobile phase;
• an autosampler fluidly connected downstream of the liquid delivery pump and configured to inject a sample into the mobile phase delivered by the liquid delivery pump;
• a separation column that is fluidly connected downstream of the autosampler and configured to separate a sample into components,
• a column oven having an internal space accommodating the separation column, a heater for heating inside of the internal space, and a temperature sensor configured to detect a temperature of the internal space, the column oven having a temperature control function of controlling a temperature of the separation column at a temperature higher than room temperature;
• a detector configured to detect the components in eluate from the separation column;
• a shutdown execution part configured to start shutdown to finally stop driving of the liquid delivery pump and temperature control operation of the column oven at a time when a predetermined situation occurs, by controlling operation of the liquid delivery pump and the column oven;
• and
• a column protection temperature setter configured to set a column protection temperature for preventing deterioration of the separation column due to overheating,
• wherein the shutdown execution part is configured to stop driving of the heater of the column oven in a state where the liquid delivery pump is driven when the shutdown is started, and then, stop driving of the liquid delivery pump after a temperature of the internal space detected by the temperature sensor becomes equal to or less than the column protection temperature,
• wherein the column oven includes a Peltier element for cooling inside of the internal space, and
• wherein the shutdown execution part is configured to drive the Peltier element to cool inside of the internal space at least until the temperature of the internal space detected by the temperature sensor reaches the column protection temperature after starting the shutdown.