Oxysterols and methods of use thereof

A compound of Formula (I-B):

• or a pharmaceutically acceptable salt thereof, wherein:
• R1 is hydrogen or substituted or unsubstituted C1-6 alkyl;
• R5 is absent or hydrogen;
• Z is —C(RA)2—, —NRB—, —O—, or —S—;
• X is halogen, substituted or unsubstituted C1-6 alkyl, or —ORC;
• RA is hydrogen, halogen, or substituted or unsubstituted C1-6 alkyl;
• RB is hydrogen, substituted or unsubstituted C1-6 alkyl, —C(O)RC, —C(O)ORC, —C(O)N(RD)2, or —S(O)2RC;
• RC is hydrogen or substituted or unsubstituted C1-6 alkyl;
• each RD is independently hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• m is an integer selected from 1, 2, and 3;
• n is an integer selected from 1, 2, and 3;
• p is an integer selected from 0, 1, 2, 3, 4, and 5;
• and
• represents a single or double bond, wherein when one is a double bond, then the other is a single bond and R5 is absent.