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US 11,884,663 B2Granted
Solid forms of emetine
AssigneeAcer Therapeutics Inc.
InventorJohn Klopp
Life of this patent
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Abstract
Crystalline forms of emetine dihydrochloride (Compound I dihydrochloride) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms of Compound I dihydrochloride.
Claims27
A crystalline form of Compound I dihydrochloride having the formula:
- selected from:
- Compound I dihydrochloride Form 7B, Compound I dihydrochloride Form 2, Compound I dihydrochloride Form 3, Compound I dihydrochloride Form 4, Compound I dihydrochloride Form 5, Compound I dihydrochloride Form 6, Compound I dihydrochloride Form 7A, and Compound I dihydrochloride Form 8.
A crystalline form of Compound I dihydrochloride having the formula:
- characterized by an X-ray powder diffractogram comprising the following peaks:
- 4.5, 9.1, 11.9, and 14.4 °2θ+0.2 °2θ, as determined on a diffractometer using Cu-Kα radiation.
Dependencies are inferred from the claim text.