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US 11,883,833 B2Granted
Dielectric materials
AssigneeBiological Dynamics, Inc.
InventorsJuan Pablo Hinestrosa Salazar, Rajaram Krishnan, Scott Conradson, Tyler Lee Harris, Robert Paul Turner, George Maroor Thomas
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Abstract
The present disclosure describes methods, devices and systems comprising materials comprising dielectrics. In various aspects, electrodes layered or imbedded with these dielectrics provide enhanced properties for a wide range of applications, such as the enhanced separation of analytes, such as biological molecules or particles (nucleic acids, viruses) with an electrokinetic field.
Claims17
A device for capturing analytes comprising:
- a) an electrode configured to generate an electrokinetic field region;
- and
- b) a layer in contact with at least a portion of the electrode, wherein the layer comprises a dielectric material of about 5 angstroms to about 25 angstroms in thickness, wherein the device increases the total yield of analyte capture as compared to a device that lacks a layer or has a layer that is more than 25 angstroms in thickness.
A method for isolating an analyte in a sample, the method comprising:
- (a) applying the sample to a device comprising an electrode configured to generate an electrokinetic field region and a layer in contact with at least a portion of the electrode, wherein the layer comprises a dielectric material of about 5 angstroms to about 25 angstroms in thickness, wherein the device increases the total yield of analyte capture as compared to a device that lacks a layer or has a layer that is more than 25 angstroms in thickness;
- (b) producing at least one AC dielectrophoretic and/or AC electrokinetic field region;
- and
- (c) isolating the analyte in the AC dielectrophoretic and/or AC electrokinetic field region.
1 more element
Dependencies are inferred from the claim text.