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US 11,883,816 B2Granted
Apparatus and method for cell, spore, or virus capture and disruption
AssigneeTang Biosciences, Inc.
InventorsJohn Richard Nobile, John F. Davidson
Life of this patent
Estimating the term…
Abstract
Embodiments disclose an apparatus and methods for biological sample processing enabling isolation and enrichment of microbial or pathogenic constituents from the sample. A vessel for sample containment and extraction is further disclosed for engagement with a transducer capable of efficient sample disruption and lysis. Together these components provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques.
Claims10
An apparatus for sample processing, comprising:
- a transducer that generates sonic or ultrasonic energy of a selected frequency, the transducer further comprising an interface having one or more surfaces which define a conical cavity within the transducer;
- and
- a sample collector having a sidewall at least partially complementary to the one or more surfaces of the interface of the transducer and that couples with the interface, wherein the sample collector is received at the transducer cavity such that sonic or ultrasonic energy generated from the transducer is propagated through the one or more surfaces of the interface into the interior portion of the sample collector.
Dependencies are inferred from the claim text.