Electroporation device with detachable needle array with lock-out system

A needle array for an electroporation device, comprising:

• a body having a locking surface and defining a central axis;
• a shroud movable with respect to the body between a rest position and one or more actuated positions;
• and
• an auto-lock including a resilient body that is coupled to and moveable with the shroud, the auto-lock being spaced from the central axis along a transverse direction that is perpendicular to the central axis, the auto-lock being adjustable between a locked configuration, where the shroud is not movable with respect to the body and a proximal end of the resilient body is deflected, and an unlocked configuration, where the shroud is movable with respect to the body, and wherein biasing the shroud from the rest position to the one or more actuated positions and back to the rest position adjusts the auto-lock from the unlocked configuration to the locked configuration, such that a bias force biases the proximal end of the resilient body along a direction that is offset from the transverse direction as the auto-lock adjusts from the unlocked configuration to the locked configuration, wherein the resilient body engages the locking surface in the locked configuration.