Stimulation design for neuromodulation
AssigneeAdvanced Neuromodulation Systems, Inc.
InventorDirk De Ridder
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Abstract
The present application relates to a new stimulation design which can be utilized to treat neurological conditions. The stimulation system produces a burst mode stimulation which alters the neuronal activity of the predetermined site, thereby treating the neurological condition or disorder. The burst stimulus comprises a plurality of groups of spike pulses having a maximum inter-spike interval of 100 milliseconds. The burst stimulus is separated by a substantially quiescent period of time between the plurality of groups of spike pulses. This inter-group interval may comprise a minimum of 5 seconds.
Claims20
A method of stimulating nerve tissue of a patient to treat a neurological disorder using an implantable pulse generator, the method comprising:
- generating, by the implantable pulse generator, a burst stimulus that comprises a plurality of groups of pulses with a quiescent period between each group in the plurality of groups, wherein:
- (i) each group of pulses begins and ends at a reference amplitude level,
- (ii) the burst stimulus is maintained at or above an amplitude level greater than the reference amplitude level between pulses within a respective group of the plurality of pulses,
- (iii) each pulse within each group is separated by an inter-pulse interval of between 0.5 to 100 milliseconds, and
- (iv) each group is separated by an inter-group interval of between 5 milliseconds and 5 seconds;
- providing the burst stimulus from the implantable pulse generator to a medical lead;
- and
- applying the burst stimulus to the nerve tissue of the patient via one or several electrodes of the medical lead.
A system to treat a neurological disorder, comprising:
- a medical lead having one or several electrodes configured to be located proximate to nerve tissue of a patient;
- a pulse generator;
- memory configured to instructions;
- one or more processors that, when executing the instructions, are configured to:
- cause the pulse generator to generate a burst stimulus that comprises a plurality of groups of pulses with a quiescent period between each group in the plurality of groups, wherein:
- (i) each group of pulses begins and ends at a reference amplitude level,
- (ii) the burst stimulus is maintained at or above an amplitude level greater than the reference amplitude level between pulses within a respective group of the plurality of pulses,
- (iii) each pulse within each group is separated by an inter-pulse interval of between 0.5 to 100 milliseconds, and
- (iv) each group is separated by an inter-group interval of between 5 milliseconds and 5 seconds;
- and
- provide the burst stimulus from the pulse generator to the one or several electrodes of the medical lead.
Dependencies are inferred from the claim text.