Event-triggered model predictive control for embedded artificial pancreas systems
AssigneePresident and Fellows of Harvard College
InventorsEyal Dassau, Francis J. Doyle, III, Stamatina Zavitsanou, Ankush Chakrabarty
Life of this patent
Estimating the term…
Abstract
The development of artificial pancreas (AP) technology for deployment in low-energy, embedded devices is contingent upon selecting an efficient control algorithm for regulating glucose in people with type 1 diabetes mellitus (T1DM). The energy consumption of the AP can be lowered by reducing updates of the control model: the number of times the decisionmaking algorithm is invoked to compute an appropriate insulin dose.
Claims19
An artificial pancreas, comprising:
- a glucose sensor configured to output glucose data related to a concentration of glucose in the bloodstream of a subject;
- an insulin pump;
- a memory containing machine readable medium comprising machine executable code having stored thereon instructions for performing a method of delivering insulin;
- and
- a control system coupled to the memory comprising one or more processors, the control system configured to execute the machine executable code to cause the processor to:
- store, in the memory, a control action for determining an amount of insulin to inject;
- receive, from the glucose sensor, a set of glucose data;
- process the set of glucose data to determine whether an update event is triggered;
- update the control action to determine a first insulin dose value if the update event has been triggered;
- determine a second insulin dose value if the update event has not been triggered, wherein the determination of the second value uses less power than the updating of the control action;
- and
- send a command to the insulin pump to deliver an amount of insulin based on either the first insulin dose value determined by the updated control action or the second insulin dose value.
A method of implementing an artificial pancreas using a control system with one or more processors, the method comprising:
- storing, in a memory, a sequence of control actions for an insulin delivery pump;
- receiving from a glucose sensor, at the control system, a set of glucose data;
- processing, by the control system, the set of glucose data to determine whether an event is triggered for updating the sequence of control actions for the insulin pump to output an updated sequence of control actions by determining a first insulin dose value from the updated sequence of control actions;
- wherein the event is not triggered,
- determining a second insulin dose value via the control system, wherein the determination of the second value uses less power than the updated sequence of control actions;
- and
- sending either the first insulin dose value or the second insulin dose value to the insulin pump.
Dependencies are inferred from the claim text.