System and method for selecting and culturing cells

A method of operating a cell processing system, the cell processing system comprising at least one processor connectable to a source container filled with a biological fluid, the at least one processor comprising a spinning membrane configured to receive and separate target cells from the biological fluid, the target cells exiting at a first outlet, at least a first container and a second container selectively connected to the first outlet, and a magnet;

• and a controller coupled to the at least one processor, the method comprising:
• operating the spinning membrane to receive biological fluid from the source container and to direct the target cells to the first container;
• pausing operation of the processor to permit magnetic particles to be associated with the target cells in the first container;
• operating the spinning membrane to receive the contents of the first container with the magnet applied to the target cells associated with the magnetic particles in the first container;
• removing and/or deactivating the magnet applied to the target cells associated with the magnetic particles in the first container;
• transferring the target cells to a second container after removal and/or deactivation of the magnet;
• and
• prompting an operator to remove the second container after the target cells are transferred to the second container.