Enhancing health in mammals using telomerase reverse transcriptase gene therapy
AssigneeSierra Sciences, Inc.
InventorsWilliam H. Andrews, Lancer K. Brown, Hamid Mohammadpour, Laura A. Briggs
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Abstract
Methods of treating an age-related disorder in a subject are provided. Aspects of the methods include administering to the subject a nucleic acid vector including a coding sequence for telomerase reverse transcriptase (TERT) and/or telomerase RNA (TR). Gene therapy methods are also provided. Aspects of the invention further include compositions, e.g., nucleic acid vectors and kits, etc., that find use in methods of the invention.
Claims17
A method of treating an age-related disorder in a subject comprising administering to the subject a nucleic acid vector comprising a coding sequence for telomerase reverse transcriptase (TERT), wherein the coding sequence is for human TERT and the vector expresses functional human TERT when present in a human cell.
A nucleic acid vector comprising a coding sequence for functional telomerase reverse transcriptase (TERT), wherein the coding sequence is for human TERT and the vector expresses functional human TERT when present in a human cell.
Dependencies are inferred from the claim text.