Nigella sativa oil composition
AssigneeN.S. Oils Ltd.
InventorsRotem Albert, Gidon Albert, Dani Rapaport, Mor Zeilkha
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Abstract
The present invention is directed to composition comprising Nigella sativa (NS) oil, wherein said oil comprises thymoquinone (TQ) at a concentration of at least 2% (w/w). The composition is further characterized by having a much lower free fatty acid concentration than prior art compositions. The composition, which has anti-inflammatory activity, may be formulated for oral administration to a mammalian subject, for the purpose of preventing or treating inflammatory conditions and other disorders.
Claims7
A unit dosage form for oral administration, comprising a composition which comprises Nigella sativa (NS) oil, an oil diluent, p- cymene and carvacrol, wherein:
- said Nigella sativa oil comprises thymoquinone (TQ) at a concentration of at least 2% (w/w) and free fatty acids (FFA), and the ratio of TQ to FFA is greater than 1.2:1;
- the ratio of TQ to p-cymene is in a range of 2.5:1-4:1;
- and
- TQ and p-cymene of said composition synergistically inhibit NO production.
Dependencies are inferred from the claim text.