Extract of Agathis robusta as antifungal agent
AssigneeKing Faisal University
InventorsMaged Elsayed Mohamed, Nancy Safwat Younis, Eman Fikry, Nora Tawfeek
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Abstract
The extract of Agathis robusta as an antifungal agent is prepared by hydrodistillation of the powdered bark of A. robusta in a Clevenger-type apparatus at 100° C. for 6 hours to obtain the essential oils of A. robusta. The essential oil is mixed with an ointment base of cholesterol, liquid paraffin, lanolin, and vaseline album, the powdered essential oil of A. robusta being added to the ointment base at 1 or 2% w/w and homogenized to a smooth ointment. When tested in vivo on Wistar rats topically infected with Candida albicans, both the 1% and 2% ointment formulations demonstrated substantial antifungal activity.
Claims5
A method of treating a fungal infection of skin, comprising topically applying an antifungal agent to the fungal infection;
- wherein the antifungal agent comprises:
- essential oils extracted from bark of Agathis robusta;
- and
- an ointment base, the essential oils extracted from the bark of Agathis robusta being mixed with the ointment base to form a homogenized ointment adapted for topical application for treatment of dermatomycoses, the essential oils extracted from the bark of Agathis robusta being between 1% w/w and 2% w/w of the homogenized ointment.
Dependencies are inferred from the claim text.