Method of preparing hematopoietic stem and progenitor cells for transplantation
AssigneeThe Board of Trustees of the University of Illinois
InventorsOwen James Tamplin, Kostandin Pajcini
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Abstract
Disclosed are methods of preparing hematopoietic stem cells and progenitor cells (HSPCs) for transplant into a subject and to methods of using the treated cells. More particularly, methods of the invention comprise treating HSPCs ex vivo with an effective amount of a GABBR1 agonist and administering the treated HSPCs to the subject.
Claims9
A method for preparing hematopoietic stem and progenitor cells (HSPCs) for transplant into a subject in need thereof comprising treating the HSPCs ex vivo with an effective amount of a GABA B receptor (GABBR) modulator thereby preparing the HSPCs for transplant into the subject.
Dependencies are inferred from the claim text.