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US 11,883,409 B2Granted
Protection of cells from degeneration and treatment of geographic atrophy
AssigneeUniversity of Kentucky Research Foundation
InventorJayakrishna Ambati
Life of this patent
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Abstract
Therapeutic uses P2X7 inhibition and inhibition of IRAK1 and/or IRAK4, methods protecting a cell, and screening methods for identifying inhibitors are described herein.
Claims14
A method of protecting a cell in a subject against degeneration or death, comprising contacting the cell with an inhibitor of MyD88, thereby inhibiting MyD88 in the cell, wherein the cell is a retinal pigmented epithelium (RPE) cell, a retinal photoreceptor, or a choroidal cell.
Dependencies are inferred from the claim text.