Fluid stimulation methods and devices for treating fluid overload
AssigneeAquapass Ltd
InventorYaacov Nitzan
Life of this patent
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Abstract
Methods for treating fluid overload in a subject comprise shifting fluids directly and non-invasively from an interstitial compartment of the subject to skin of the subject through controlled local sweating. Methods of the invention allow for removal of excess fluid from the interstitial compartment of the subject and treat fluid overload in the subject. Sweat stimulation systems comprise a chamber and first and second relative humidity sensors. The chamber is sized to fit around a body part of a subject, comprises an inlet and an outlet, and is configured such that air flows through the chamber from the inlet to the outlet. The first relative humidity sensor is operably located inside the inlet, and the second relative humidity sensor is operably located proximate the outlet.
Claims33
A fluid stimulation system comprising:
- a mobile, wearable apparatus comprising a chamber sized to fit around a body part of a subject and to stimulate fluid loss in the subject, wherein at least a portion of the chamber provides a clear volume of air between the body part and one or more walls of the chamber upon receipt of air flow and subsequent expansion of the chamber, the chamber comprising an inlet and an outlet and the chamber being configured such that an air flow passes through the chamber from the inlet to the outlet to thereby create a controlled environment around the body part of the subject for stimulating fluid loss in the subject;
- first and second relative humidity and temperature sensors, wherein the first relative humidity sensor is operably located at the inlet and the second relative humidity sensor is operably located proximate the outlet;
- and
- a controller communicatively coupled with at least the first and second relative humidity and temperature sensors and configured to monitor and control conditions of the controlled environment around the body part of the subject based, at least in part, on data received from the first and second relatively humidity and temperature sensors, the controller being configured to control and adjust inflow air temperature and air flow rate into the chamber so as to maintain a temperature of the environment within the chamber between 32° C. and 50° C., maintain a relative humidity of the environment within the chamber at less than 50%, and maintain an air flow rate of between 0.2 cubic meters per minute and 4 cubic meters per minute.
A method for treating fluid overload in a subject, the method comprising:
- shifting fluids directly and non-invasively from an interstitial compartment of the subject to skin of the subject through controlled local fluid loss, thereby removing excess fluid from the interstitial compartment of the subject and treating fluid overload in the subject,
- wherein the fluid loss is sweating stimulated by controlling an environment, including relative humidity, airflow, pressure, and temperature of the environment, within a chamber of a mobile, wearable apparatus fitted around a body part of a subject, said environment being monitored and controlled by a controller configured to control and adjust inflow air temperature and air flow rate into the chamber so as to maintain a temperature of the environment within the chamber between 32° C. and 50° C., maintain a relative humidity of the environment within the chamber at less than 50%, and maintain an air flow rate of between 0.2 cubic meters per minute and 4 cubic meters per minute.
A method of removing fluids through the skin by osmosis comprising:
- providing a mobile, wearable apparatus comprising a chamber sized to fit around a body part of a patient;
- fitting the chamber around a body part of a patient, the chamber comprising interstitial electrolytes;
- and
- controlling content and concentration of at least the interstitial electrolytes in the chamber, thereby driving water and salts out of the body part of the patient while maintaining pH and electrolyte levels of the body part.
A method to reduce edema by enhancing fluid transfer through skin of a patient wearing a mobile, wearable apparatus comprising a chamber fitted around a body part of the patient, wherein the enhancing fluid transfer is controlled by a smartphone application operably associated with at least the chamber and configured to control air flow through the chamber to thereby control fluid transfer through the skin of the patient.
A system to reduce edema by enhancing fluid transfer through skin of a patient, wherein the system comprises a mobile, wearable apparatus comprising a chamber sized to fit around a body part of the patient and is controlled by a smartphone application operably associated with at least the chamber and configured to control air flow through the chamber to thereby control fluid transfer through the skin of the patient.
A method for treating fluid overload in a subject, the method comprising:
- shifting fluids directly and non-invasively from an interstitial compartment of the subject to skin of the subject through controlled local fluid loss, thereby removing excess fluid from the interstitial compartment of the subject and treating fluid overload in the subject,
- wherein the fluid loss is sweating that is stimulated by controlling an environment and elevating skin temperature of the subject within a chamber of a mobile, wearable apparatus fitted around a body part of a subject, said environment being monitored and controlled by a controller configured to control and adjust inflow air temperature and air flow rate into the chamber so as to maintain a temperature of the environment within the chamber between 32° C. and 50° C. and maintain an air flow rate of between 0.2 cubic meters per minute and 4 cubic meters per minute.
Dependencies are inferred from the claim text.