In vivo tissue engineering devices, methods and regenerative and cellular medicine employing scaffolds made of absorbable material

An implantable prosthesis comprising:

• a tissue infiltratable scaffold of biocompatible material having a proximal end, a distal end spaced from the proximal end, and a hollow core extending through the scaffold along a core axis from the proximal end to the distal end, the scaffold including a plurality of chambers circumferentially arranged around the core axis, each of the plurality of chambers extending in a corresponding outward radial direction away from the hollow core, the scaffold further including a proximal opening at the proximal end and a distal opening at the distal end, the proximal and distal openings being aligned with each end of the hollow core to allow access to the hollow core;
• and
• a first layer of biocompatible material located at the proximal end of the scaffold, the first layer being oriented in a direction transverse to the core axis and having a first opening aligned with the proximal opening of the scaffold to permit access to the hollow core from the proximal end.