US 11,882,858 B2 · Composition for skin whitening comprising β-mangostin as effective ingredient

Abstract

A skin whitening composition includes β-mangostin or a cosmetically acceptable salt thereof as an effective ingredient. β-Mangostin represented by Chemical Formula 1 suppresses the expression of tyrosinase and TRP-1 (tyrosinase-related protein-1) and induces autophagy of a melasosome. As such, it was confirmed that the β-mangostin not only suppresses melanin production but also exhibits the effect of removing previously formed melanin. Accordingly, the β-mangostin can be advantageously used as a functional material for skin whitening and skin lightening.

Claims3

Dependent claims

A method of whitening a skin, comprising:

isolating β-mangostin by extracting seedcases of a mangosteen with chloroform, the β-mangostin represented by the following chemical formula 1;
preparing a cosmetic composition comprising:
the β-mangostin or a cosmetically acceptable salt thereof as an effective ingredient;
less than 20 μM of α-mangostin;
and
less than 40 μM of γ-mangostin;
and
applying the cosmetic composition to the skin.

5 more elements

Dependencies are inferred from the claim text.

Composition for skin whitening comprising β-mangostin as effective ingredient

Life of this patent

Composition for skin whitening comprising β-mangostin as effective ingredient

Life of this patent

Abstract

Claims3