Method and composition comprising detoxified lipopolysaccharide and lipoteichoic acid for preventing or inhibiting formation of biofilm
AssigneesSogang University Research & Business Development Foundation, Korea Food & Drug Administration
InventorsKyu-Ho Lee, Hyo-Sun Kwak, Youchul Jung, Kyung Jo Lee, Jeong-A Kim, Boram Jang, Sebin Kang
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Abstract
Provided is a novel bacterial strain Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) and its use. The LPS from the strain of the subject matter has cytotoxicity weaker than the conventional ones and shows synergistic effect on the inhibition of biofilm formation when used in combination with LTA.
Claims7
A method of inhibiting or preventing biofilm formation comprising contacting the composition with Gram-positive or Gram-negative bacteria, wherein the composition comprises dLPS (deacylated Lipopolysaccharide) and dLTA (deacylated Lipoteichoic acid) in combination, wherein the dLPS is from Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) strain deposited as KCTC13624BP at Korean Collection for Type Cultures.
Dependencies are inferred from the claim text.